Upon detecting increase of cholesterol, these receptors activate signaling pathways that remove the diet-derived cholesterol from the body. Two types of LXRs – LXR-alpha and LXR-beta – are therefore potential targets for development of anti-atherosclerosis drugs. However, the effects of synthetic drugs that activate these two receptors have been studied well. In a study, online in advance of publication in the August print issue of the Journal of Clinical Investigation, show Peter Tontonoz and colleagues from the University of California, Los Angeles, supports the idea LXR-beta by a synthetic compound is able to reverse atherosclerosis, and cholesterol overload in mice..

TITLE: SLAT regulates Th1 and Th2 inflammatory responses by controlling Ca2+ / NFAT signalingAUTHOR: Amnon Altman, La Jolla Institute for Allergy and Immunology, La Jolla, California,macrophages in the spleen regulate the immune response and immune toleranceautoimmune diseases such as multiple sclerosis and arthritis resulting from the body’s immune system to attack its own tissues , or self – antigens . Therefore, researchers have long wanted to understand how a state of immune tolerance can be forced a therapeutic approach a therapeutic approach for the treatment of autoimmune diseases are induced. Tolerance in a study that examined online in advance of publication in the August print issue of the Journal of Clinical Investigation, Masato Tanaka and colleagues from RIKEN Research Center for Allergy and Immunology in Japan, the contribution of cells in the spleen as macrophages known establishing immunological..Opinion, emerging destiny of the Neanderthal.

As this debate strengthened during the last decades, it has been the central research main focus Erik Trinkaus, professor of anthropology at Washington University in St. Trinkaus is which early modern humans in Europe, including the sample Romania, the Czech Republic and France studied. Such samples, at Trinkaus’ opinion, clearly have Neanderthal man ancestors demonstrated.