Monthly Archives: January 2018

A kind of cold virus.

But E4-ORF3 is the virus’s Swiss army knife – it assembles into a thing that is highly versatile. It has the capacity to build itself into all sorts of different sizes and shapes that can capture and deactivate the many defenses of a bunch cell. In collaboration with researchers from the National Center for Imaging and Microscopy Analysis at University of California, NORTH PARK, led by Tag Ellisman, the center’s director, O’Shea’s team used new techniques to reveal the ultrastructure of the impressive polymer that E4-ORF3 assembles in the nucleus – a thing that previously had confirmed difficult since the polymer is efficiently invisible using typical electron microscopy. Continue reading