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The compounds appear to be being among the most promising potential remedies for prion diseases yet discovered, the record suggests.. Aminothiazoles as therapeutic potential clients for prion diseases Scientists who examined a lot more than 10,000 chemical substances over the last year searching for potential new medicines for a group of untreatable brain diseases, are reporting that 1 substance shows unusual promise. The early positive signals for so-called prion diseases come from study in laboratory mice and cell cultures, they state in a written report in ACS’ Journal of Medicinal Chemistry. Adam Renslo and colleagues, who consist of Nobel Laureate Stanley B.