We and Astellas will continue to work carefully with the medical trial site, the DSMB and the FDA to examine this serious adverse event, and look for to resume patient enrollment and treatment in the Action 5 study the moment it is appropriate to do so. .. Astellas suspends enrollment in Take action 5 research of KYNAPID in atrial fibrillation patients Cardiome Pharma Corp. today announced that its co-development partner, Astellas Pharma US., Inc., has suspended individual enrollment in the ACT 5 study of KYNAPIDTM Injection carrying out a single unexpected severe adverse event of cardiogenic shock experienced by a patient with atrial fibrillation who received KYNAPID.Actually, a true organic trigger is identified in mere a small percent of kids who wet the bed. However, this will not mean that the kid who wets the bed can control it or does it on purpose. Kids who wet the bed aren’t lazy, willful, or disobedient. There are two types of bedwetting: principal and secondary. Principal bedwetting identifies bedwetting that is ongoing since early childhood with out a break. A kid with primary bedwetting hasn’t been dry during the night for any significant amount of time. Secondary bedwetting is usually bedwetting that starts once again after the kid has been dry during the night for a significant time period . In general, principal bedwetting indicates immaturity of the nervous program probably.